I use HDT for Bodyslide 2 as naked body shape, the new Remodeled Armor HDT Beta for Bodyslide 2 as vanilla outfit replacer and in addition several other TBBP able outfits and a few HDT outfit conversions. It needs to have special weightings to work flawlessly. HDT PE is not totally independent of the body mesh you use. but you aren't the first one that reports issues to get HDT PE running with the CHSBHC body. and yes, if you use that skeleton you don't have to remove anything from that folder, especially no. In addition I run the same stuff concerning scripts: SKSE 1.07 alpha, Race Menu scripts, SKSE.ini, Netimmerseoverride, SafetyLoad, Fuz Ro D'oh etc. I even run an ENB (with v14.28 you don't need to make any adjustments anymore in the ENB GUI, aka WaitBusyRenderer= etc.). HDT PE runs flawlessly on my system, no crashes, no mesh deformations, no issues at all.

Groovtama's XMPS 1.93 Rev 50 Extended solved it, totally. I installed HDT PE 14.28 + HDT Body for Bodyslide 2 v1.4 a few days ago and had the twitching issue for a short while too.

Hdt physics extension steam